Emission inventory of HCFC-141b in China was established based on the IPCC Guidelines for National Greenhouse Gas Inventories (2006). Constitution and trend of HCFC-141b emission was analyzed. The product retire emission, which considered to be the largest part of emission, accounts for 48.7% of the total; under Montreal Protocol Phaseout Schedule (MPPS) and Accelerated Phaseout Schedule (APS) scenarios, total ODP emission reduction would be 7.30×10⁴ tons and 7.46×10⁴ tons ODP and GHG emission reduction would be 4.7317×10⁸ tons and 4.8381×10⁸ tons CO₂-eq respectively during 2010-2030; compared to the MPPS scenario, the APS scenario result in additional 3.815×10⁷ tons CO₂-eq GHG emission reduction during HCFC-141b emission period and most of the reduction comes from refrigerator, water heater insulation and panel sub-sector. China makes great contribution on global GHGs reduction during the implementation of Montreal Protocol.